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Filtered Search Results
Medchemexpress LLC 2,4-dichlorophenoxyacetic acid | 94-75-7 | 99.9% | 221.04 | 250 MG
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2,4-D (Standard) is an analytical standard intended for research and analytical applications. Also known as 2,4-dichlorophenoxyacetic acid, it acts as a selective herbicide for broad-leaved weed control. This compound induces apoptosis and inhibits DNA and protein synthesis, preventing normal plant growth and development.
- Analytical standard for research and analytical applications
- Selective herbicide for broad-leaved weed control
- Induces apoptosis and inhibits DNA and protein synthesis
- Used in qualitative, quantitative and methodological research experiments in HPLC, GC, and MS
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Medchemexpress LLC 2-Ethyl-6-methylaniline-d13 | 1219794-93-0 | 98.6% | 148.29 | 25 MG
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2-Ethyl-6-methylaniline-d13 is the deuterium labeled 2-Ethyl-6-methylaniline. It serves as a tracer and an internal standard for quantitative analysis. The incorporation of stable heavy isotopes into drug molecules, known as deuteration, aids in quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules.
- Aids in quantitation during drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC KIF18A-IN-6 | 2914879-10-8 | C28H37N3O5S2 | 250 MG
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KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity. It demonstrates anti-proliferative effects on JIMT-1, HCC-15, and NIH-OVCAR3 cells in vitro and exhibits significant tumor growth inhibition in HCC15 and OVCAR3 xenograft models in mice. This product is for research use only.
- Orally active KIF18A inhibitor
- High potency against KIF18A microtubule-dependent ATPase activity (IC50 of 0.016 μM)
- Demonstrates anti-proliferative effects on cells in vitro
- Exhibits significant tumor growth inhibition in xenograft models in mice
- Multiple packaging options cater to different research needs
- Comprehensive documentation ensures quality assurance and provides essential information for researchers
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Medchemexpress LLC Methyl 4-boronobenzoate | 99768-12-4 | 179.97 | 25 G
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Methyl 4-boronobenzoate, also known as 4-Methoxycarbonylbenzeneboronic acid, is a biochemical reagent used as a biological material or organic compound in life science research. It should be stored as powder at -20°C for 3 years or 4°C for 2 years. In solvent, store at -80°C for 6 months or -20°C for 1 month.
- Used in tandem-type Pd(II)-catalyzed oxidative Heck reactions.
- A reagent for intramolecular CH amidation sequences.
- Employed in copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids.
- Applicable in one-pot ipso-nitration of arylboronic acids.
- Used in palladium-phosphine-catalyzed Suzuki-Miyaura coupling.
- Employed in the preparation of biaryls via nickel-catalyzed Suzuki-Miyaura cross-coupling.
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Medchemexpress LLC Methanesulfonothioic acid, S-methyl ester | 2949-92-0 | 126.20 | 25 G
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S-Methyl thiomethanesulfonate (MMTS) is a sulfur-containing volatile organic compound produced by plants and bacteria and is an effective anti-oomycete agent.
- Effective anti-oomycete agent.
- Sulfur-containing volatile organic compound.
- Produced by plants and bacteria.
- Molecular weight: 126.20.
- Purity: 99.9%.
- Appearance: Colorless to light yellow liquid.
- Pure form storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC 4-Methylbenzylidene camphor | 36861-47-9 | 99.87% | 254.37 | 250 MG
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4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. It decreases the proliferation of human trophoblast cells and induces apoptosis. It also activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-MBC functions as a ultraviolet (UV) filter and may hinder normal placental formation during early pregnancy. This product is for research use only and not intended for human use.
- Endocrine disrupter with estrogen-like effects.
- Decreases proliferation and induces apoptosis in human trophoblast cells.
- Activates PI3K/AKT and ERK1/2 signaling pathways.
- Elevates intracellular ROS production.
- Functions as a ultraviolet (UV) filter.
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Medchemexpress LLC Avanafil impurity 2 hydrobromide | 859517-85-4 | 250mg
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Avanafil impurity 2 hydrobromide is an impurity of Avanafil (HY-18252)
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Medchemexpress LLC Adamantanine (2-aminoadamantane-2-carboxylic acid) | 42381-05-5 | ≥97.0% | 250 MG
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Adamantanine (2-aminoadamantane-2-carboxylic acid) is a small-molecule research compound used to probe amino acid transport and aminopeptidase-related pathways in cellular and biochemical studies.
- CAS number 42381-05-5
- Molecular formula C11H17NO2
- Molecular weight 195.26 g/mol
- Purity ≥97.0%
- Appearance solid, off-white to yellow
- Available in 50 mg-5 g packs; 10 g and 50 g available by quote
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month)
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Medchemexpress LLC Methyl clofenapate | 21340-68-1 | 99.0% | 304.77 | 25 MG
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Methyl clofenapate is a chemical compound supplied as a white to off-white solid. It is primarily used as a laboratory chemical for research purposes and the manufacture of substances, exhibiting good stability under recommended storage conditions.
- For research use only
- Stable under recommended storage conditions
- Supplied as a solid (white to off-white)
- High purity (99.04%)
- Recommended storage for powder: -20°C for 3 years; 4°C for 2 years
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eMolecules Ambeed 2 5 6-Trichloronicotinamide 250mg 490541332 A239000 0 000 142266-62-4 MFCD22493418 225 450 C6H3Cl3N2O
Ambeed 2 5 6-Trichloronicotinamide 250mg 490541332 A239000 0 000 142266-62-4 MFCD22493418 225 450 C6H3Cl3N2O
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Medchemexpress LLC (R)-Exatecan Intermediate 1 | 110351-91-2 | 99.9% | 263.25 | 250 MG
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(R)-Exatecan Intermediate 1 is a crucial intermediate used in the synthesis of Camptothecin derivatives, and it can be utilized to prepare Exatecan mesylate. This intermediate facilitates the synthesis of Exatecan, a compound known for its low sensitivity to multidrug resistance and its significant value in anti-tumor research.
- Key intermediate in the synthesis of Camptothecin derivatives.
- Can be used to prepare Exatecan mesylate.
- Enables the synthesis of Exatecan.
- Exatecan exhibits low sensitivity to multidrug resistance.
- Valuable for anti-tumor research.
- Available in solid and solution forms.
- High purity: 99.95%.
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Medchemexpress LLC N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide | 329198-87-0 | 99.5% | 322.27 g/mol | C17H10N2O5 | 250MG
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C-178 is a potent, selective, covalent small-molecule inhibitor of the Stimulator of Interferon Genes (STING). It covalently modifies Cys91 on mouse STING, blocking palmitoylation and downstream signaling; the compound is active in mouse models but shows little to no activity against human STING. Supplied as a research-grade compound for preclinical studies; not for human or veterinary use.
- Covalent inhibitor of STING that binds Cys91.
- Selective activity in mouse STING assays, not active on human STING.
- Molecular formula C17H10N2O5 and molecular weight 322.27 g/mol.
- High purity, typically ≥99% by HPLC.
- Appearance: yellow to orange solid; soluble in DMSO.
- Mechanism blocks STING palmitoylation and downstream signaling events.
- Intended for research use only; not for clinical use.
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Medchemexpress LLC 6-O-Methyl-guanine | 20535-83-5 | 98.9% | 165.16 | 25 G
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6-O-Methyl-guanine is a biochemical reagent suitable for life science related research. It is intended for research use only.
- Solid, white to off-white appearance
- Ships at room temperature in the continental US
- Store at 4°C, protected from light
- For storage in solvent, keep at -80°C for 6 months or -20°C for 1 month, protected from light
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Medchemexpress LLC Ethyl 3,4,5-trimethoxybenzoate | 6178-44-5 | 99.7% | 240.26 | 1 ML
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Ethyl 3,4,5-trimethoxybenzoate is a natural compound isolated from the roots of Rauvolfia yunnanensis Tsiang. It is intended for research use only.
- Natural compound
- Isolated from Rauvolfia yunnanensis Tsiang roots
- For research use only
- High purity (99.67%)
- Molecular weight of 240.26
- Appears as a white to off-white solid
- Soluble in DMSO (≥ 100 mg/mL)
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Medchemexpress LLC Methanone, (4-amino-1,3-dihydrofuro[3,4-c]naphthyridin-8-yl)[(3S)-3-[4-(trifluoromethyl)phenyl]-4-morpholiny | 2790567-82-5 | C22H19F3N4O3 | 250 MG
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AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. When complexed with MTA, it preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5, while protecting normal cells with wild-type MTAP. This compound is for research use only.
- Preferentially inhibits the growth of MTAP-deficient tumor cells
- Inhibits PRMT5 with an IC50 of 0.107 μM
- Protects normal cells with wild-type MTAP
- Induces alternative splicing defects, cell cycle arrest, and DNA damage response in MTAP-deficient HCT116 cells
- Reduces S phase and increases G2/M cell population in MTAP-deficient cells
- Dose-dependently inhibits tumor growth in MTAP-deficient xenograft mice
- Causes tumor regression in 70% of mice with DLBCL tumors
- Preserves normal hematopoietic cell lineages
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